Sarcoma (Osteosarcoma Ewing's Sarcoma Rhabdmyosarcoma) Renal Tumors ( Wilm's and others) Hepatoblastoma Cancer predisposition syndromes
Bio
Dr. Austin is a member of the American Society of Pediatric Hematology-Oncology, American Society of Hematology, Children’s Oncology Group, American Society of Clinical Oncology and International Society of Paediatric Oncology.
Education
Medical School
Drexel University School of Medicine, Philadelphia, PA
Residency
St. Christopher's Hospital for Children, Philadelphia, PA
Fellowship
Children's Hospital of Richmond at VCU
Research interests
Molecular biology of solid tumors
Publications
C Yang, F Austin, H Richard, M Idowa, V Williamson, F Sabato, A Ferrerira-Gonzalex, SA Turner. Lynch Syndromrome Associated ultra hypermutated pediatric glioblastoma mimicking a constitutional mismatch repair deficiency syndrome. Cold Spring Harb Mol Case Study. 2019 Oct 23:5(5). pii: a003863. doi: 10.1101/mcs.a003863.
F Austin, U Oyarbide, G Massey, M Grimes, S Corey. Synonymous mutation in TP53 results in cryptic splice site affecting its DNA binding site in an adolescent with two primary sarcomas. Pediatric Blood & Cancer. Pediatr Blood Cancer. 2017 Nov;64(11). doi: 10.1002/pbc.26584. Epub 2017 May 5.
PL Wagner, F Austin, M Zenati, A Mavanur, L Ramalingam, H Jones, M P Holtzman, S Ahrendt, AH Zureikat, JF Pingpank, HJ Zeh, DL Bartlett, H Choudry. Oncologic Risk Stratification Following Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy for Appendiceal Carcinomatosis. Ann Surg Oncol. 2016 May;23(5):1587-93. doi: 10.1245/s10434-015-5037-7.
D Magge, MS Zenati, F Austin, A Mavanur, M Sathaiah, L Ramalingam, H Jones, AH Zureikat, M Holtzman, S Ahrendt, J Pingpank, HJ Zeh, DL Bartlett, HA Choudry. Malignant peritoneal mesothelioma: prognostic factors and oncologic outcome analysis. Ann Surg Oncol. 2014 Apr;21(4):1159-65. doi: 10.1245/s10434-013-3358-y.
P Thirunavukarasu, M Sathaiah, MC Gorry , ME O'Malley, R Ravindranathan, F Austin, SH Thorne, ZS Guo, DL Bartlett. A rationally designed A34R mutant oncolytic poxvirus: improved efficacy in peritoneal carcinomatosis. Mol Ther. 2013 May;21(5):1024-33. doi: 10.1038/mt.2013.27.
PL Wagner, F Austin, U Maduekwe, A Mavanur, L Ramalingam, HL Jones, MP Holtzman, SA Ahrendt, AH Zureikat, JF Pingpank, HJ Zeh, DL Bartlett, HA Choudry. Extensive cytoreductive surgery for appendiceal carcinomatosis: morbidity, mortality, and survival. Ann Surg Oncol. 2013 Apr;20(4):1056-62. doi: 10.1245/s10434-012-2791-7.
PL Wagner, F Austin, M Sathaiah, D Magge, U Maduekwe, L Ramalingam, HL Jones, MP Holtzman, SA Ahrendt, AH Zureikat, JF Pingpank, HJ Zeh 3rd, DL Bartlett, HA Choudry. Significance of serum tumor marker levels in peritoneal carcinomatosis of appendiceal origin. Ann Surg Oncol. 2013 Feb;20(2):506-14. doi: 10.1245/s10434-012-2627-5
F Austin, A Mavanur, M Sathaiah, J Steel, D Lanzner, L Ramalingam, M Holtzman, S Ahrent, J Pingpank, HJ Zeh, DL Bartlett, HA Choudry. Aggressive management of peritoneal carcinomatosis from mucinous appendiceal neoplasms. Ann Surg Oncol. 2012 May; 19(5):1386-93.
M Sathaiah, P Thirunavukkarasu, ME O'Malley, MA Kavanagh, R Ravindranathan, F Austin, ZS Guo, DL Bartlett. Oncolytic poxvirus armed with Fas ligand leads to induction of cellular Fas receptor and selective viral replication in FasR-negative cancer. Cancer Gene Ther. 2012 March; 19(3):192-201.
ZS Guo, V Parimi, ME O'Malley, P Thirunavukarasu, M Sathaiah, F Austin, DL Bartlett. The combination of immunosuppression and carrier cells significantly enhances the efficacy of oncolytic poxvirus in the pre-immunized host. Gene Ther. 2010 December; 17(12):1465-75.
MF Ziauddin, ZS Guo, ME O’Malley, F Austin, PJ Popovic, MA Kavanagh, J Li, M Sathaiah, P Thirunavukkarasu, B Fang, YJ Lee, and DL Bartlett. TRAIL gene-armed oncolytic poxvirus and oxaliplatin can work synergistically against colorectal Cancer. Gene Ther. 2010 April; 17(4):550–559.
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